The Ethics Committee of Renmin Hospital of Wuhan University approved the present study. All experiments involving human samples were performed in accordance with the principles of the Declaration of Helsinki. All participators provided written informed consent. A total of 67 pairs of cervical cancer tissues and matched adjacent normal tissues were acquired from the patients at Renmin Hospital of Wuhan University. No patient had undergone chemotherapy, radiotherapy, or other anticancer treatments prior to surgical resection. Immediately after tissue excision, all tissues were stored in liquid nitrogen until further analysis.

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