The enrolled subjects included patients with cervical intraepithelial neoplasia (CIN) and CC. Patients were diagnosed and treated at the Department of Gynecology of The First Affiliated Hospital of Soochow University (Suzhou, China) between January 2019 and June 2020. In this study, patients with other malignant tumors or history of treatment for other malignant tumors were excluded. The clinical and pathological data were collected. Patients with other benign tumors who underwent total hysterectomy were assigned as controls. The cervical pathological diagnosis was normal in the controls. Written informed consent was obtained from all patients, and the study was approved by the Ethics Committee of The First Affiliated Hospital of Soochow University (approval no. 2020LS265).

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