AF progression was defined as paroxysmal AF that developed into persistent or permanent AF, or persistent AF that developed into permanent AF. The time to AF progression was the time to development of persistent AF or electrical cardioversion or permanent AF. Follow-up visits were planned 3 monthly during the first year, thereafter yearly. If AF patients visited the treating cardiologist in the meantime, information from the medical records was collected and change of AF type was noted. Treatment after inclusion in the registry was not specified in the study protocols and led to discretion of the treating physician. The follow-up period started at the inclusion date (first inclusion November 2009) and was continued until the most sustained type of AF progression, the last contact date (last patient December 2017), or until death, with a maximum follow-up duration of 60 months.

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