In order to compare phenotypes of INF isolates CloNo isolates, we used mixed models with the individual patient as random intercept. To analyse metric variables, a linear mixed model was used. Variables were log10-transformed where appropriate, in order to attain symmetrically distributed values and residues. Results are reported as either mean effect size between INF and CloNo isolates or in case of log-transformed variables, as a factor (10 to the power of co-efficient). P-value and 95% confidence interval of mean effect size or factor are given. Categorical variables were analysed in a mixed ordinal regression model. Results are reported as odds ratio (OR), 95% confidence interval of OR and p-value. Statistical significance was accepted at a p-value <0.05. Analyses were conducted in SPSS version 25 (IBM, Armonk, NY, USA).

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