Results are shown as mean ± SD. Real-time RT-PCR mRNA and ChIP data were analyzed by one-way analysis of variance (ANOVA) and post hoc comparisons (Fisher’s protected least significant difference test), whereas DNA methylation data were analyzed by Fisher’s exact test (for small sample size) or χ2 test (for bigger sample size), using Statview® (SAS institute, NC) software. We assessed statistical significance at p < 0.05.

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