This study was a two-arm RCT with a primary aim of studying the effect of increased cod intake during pregnancy on maternal iodine status, and a secondary aim of determining infant neurodevelopment when the children were 11 months old. Participants were recruited through the Women's Clinic at Haukeland University Hospital, Health region West, Norway. Approximately 5000 women give birth at the Women's Clinic annually. Once a pregnant woman was enrolled, the study investigators made every reasonable effort to follow the participant closely for the entire trial period to ensure the best possible retention. Before all the visits, the participants were reminded about the upcoming appointment.

From January 2016 until February 2017, information regarding the intervention trial was included in the invitation from the Women's Clinic at the time of routine ultrasound in gestational week 18. To increase the enrollment rate, information regarding the trial and invitation to participate were also broadcasted online (Facebook, Instagram, and in an online magazine for pregnant women in Norway). Pregnant women who were interested in the study contacted the researchers at the Institute of Marine Research (IMR), Bergen, Norway.

Inclusion criteria were primiparous singleton pregnancy, gestational week ≤19, and Norwegian speaking and/or understand Norwegian writing. Exclusion criteria were allergies to fish and chronic diseases known to affect iodine status (Graves' disease, thyroiditis, thyroid nodules, known hypothyroidism or hyperthyroidism). Participants gave written informed consent after receiving written and oral information about the study. No specific information about iodine was given as the overall aim of the study was to study the relationship between Mommy's Food (nutrient intake in pregnancy and the infants' first year) and infant development. The women could withdraw from the study at any time without giving any reason. The trial complies with the Declaration of Helsinki and was approved by the Regional Committee for Medical and Health Research Ethics West (2015/879). The study protocol has been published elsewhere (18).

Note: The content above has been extracted from a research article, so it may not display correctly.

Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.

We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.