We presented categorical variables as numbers and percentages and performed comparisons between groups using Fisher’s exact tests. In case of significant differences between multiple groups, we carried out pairwise post hoc tests. Adjusted p-values were calculated using the ‘Holm’ method to account for multiple comparisons. We considered p-values < 0.05 as statistically significant. We performed all statistical analyses using the R software version 3.5.1 R core team 2018 (Vienna, Austria; https://www.R-project.org/).

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