Infertility patients were recruited from the Reproductive Medicine Center of Women's Hospital of Nanjing Medical University and The First Affiliated Hospital of Nanjing Medical University. All samples from donors were obtained with informed consent. This study was approved by the Ethics Committee of the Nanjing Medical University (2018/651), the Ethics Committee of Women's Hospital of Nanjing Medical University (KY-025) and the Ethics Committee of The First Affiliated Hospital of Nanjing Medical University (2012-SR-128).

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