Gene Ontology and Kyoto Encyclopedia of Genes and Genomes Analysis

The DAVID database (https://david.ncifcrf.gov/) [9] was used to carry out Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) enrichment analysis of identified DEGs, including those associated with molecular functions, cellular components, and biological processes [10]. GO terms and KEGG pathways with P<0.05 were selected as significant.

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