To determine the safety of intraarticular UC-derived WJ formulation (GeneXSTEMTM).

To assess change in patient-reported outcome measures, NPRS and KOOS, from baseline to various follow-up time points.

To assess cartilage formation via MOCART at the 1-year time point and compare if from baseline.

To assess patient satisfaction using SF-36, 7-point Likert scale and Single Assessment Numeric Evaluation (SANE).

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