In this experiment, the rats were sacrificed and whole blood was collected. The red blood cells (RBC), white blood cells (WBC), platelets (PLT) and haemoglobin (HGB) were detected using the animal haematology analyser (950FS, Drew Scientific, USA). Serum samples were obtained by centrifuging 2 ml of whole blood at 2500 r.p.m. for 15 min. Creatinine, urea nitrogen, glutamic-pyruvic and glutamic oxalacetic transaminase were detected by the automatic biochemical analyser (TRI-9002, Trilogy, USA).

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