To verify the power of the PRG signature, patients with ICC were divided into high- and low-risk groups based on the median risk scores in the training, testing, and entire sets. OS was compared in high- and low-risk groups using Kaplan–Meier analysis. Survival analysis was also conducted using each of the PRGs in the training and testing sets. Receiver operating characteristic (ROC) curve analysis based on the risk scores of PRGs was performed in the three sets with R package “survivalROC” (arguments: method = KM), and the value of the area under the curve (AUC) was determined to verify the model sensitivity and accuracy. Finally, the survival status map showed the distribution of death endpoint events based on the risk scores of PRGs.

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