The time-dependent killing for S. aureus ATCC 29213 and MRSA 43300 with IBG, VAN at 10 × MIC was investigated previously (AbdelKhalek et al., 2016). The OD600nm was measured to determine bacterial lysis when S. aureus (OD600nm ∼0.4) treated with 10 × MIC of IBG, VAN, and BAC (positive control) for 4 h (Kim et al., 2018). All the experiments were replicated.

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