Continuous variables were expressed as median (25th, 75th percentile), whereas categorical variables were reported as number (%). Non-parametric statistics or Chi-square test was used to compare the index variables between subjects with or without worsened BP. Paired t test was used to examine differences in variables between subjects between index and following visits. Multivariate logistic analysis was performed to investigate the associations between plasma concentrations of SCFAs and worsening renal and cardiovascular parameters (worsened BP, increased LV mass, increased LVMI, reduced EF, increased IMT, increased PWV, decreased eGFR). SPSS version 22.0 (SPSS, Inc., Chicago, IL, USA) was used for all analyses.

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