The protocol of this review was submitted to The International Prospective Register of Systematic Reviews (PROSPERO) on 30/3/2020 (ID 172044)13. PubMed and Embase were searched on 30/03/2020 for original study reports. Articles containing subsequent quantitative cerebral aneurysm motion measurements within one cardiac cycle were included. The search strategies were composed together with an experienced Liberian (Appendix A). No date or language restrictions were applied. The exclusion criteria were (1) No original study paper (i.e. conference abstracts, letters, case reports and reviews), (2) animal and ex-vivo studies, (3) Ruptured or treated cerebral aneurysms, and (4) No description of aneurysm measures of size, dimensions, volumes, morphology, amplitudes or wall motion/movement, over one or more cardiac cycles in the abstract.

The screening was performed by two reviewers (L.B.S. and R.A.) using the Rayyan online screening tool (, last accessed: 2020-04-05)14. Both reviewers were blinded to each other’s decisions. After each screening phase, conflicts were discussed and resolved.

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