Number of episodes of neurological deterioration in both groups of patients during the 12 days of treatment (Supplemental data 1).

Symptoms associated with TBI in both groups of patients during the 12 days of treatment.

Volume of pericontusional edema before and after 12 days of treatment in both groups of patients.

Presence of adverse events between the 2 groups during the 12 days of treatment.

Neuropsychological tests between the 2 groups of patients one month and 6 months after the TBI.

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