2.1. Trial design and registration
This protocol is extracted from research article:
Lipi Guben decoction in treating diarrheal irritable bowel syndrome
Medicine (Baltimore), Jan 22, 2021; DOI: 10.1097/MD.0000000000023887

This is a RCT. Participants will be recruited from the outpatient clinics of the First Affiliated Hospital of Guizhou University of TCM. The Figure Figure11 shows the study design in the flowchart, and the Figure Figure22 illustrates the time schedule of enrolment, interventions, assessments, and visits of participants. The reporting of this trial is conducted according to the Standard Protocol Items: Recommendations for Intervention Trials (SPIRIT) guidelines (Additional file 1).

Study flow diagram.

Study design schedule.

This protocol has been registered in the Chinese Clinical Trial Registry on November 3,2020, http://www.chictr.org.cn/edit.aspx?pid=63618&htm=4. And the registration number is ChiCTR2000039617.

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