The anti-tumor effect of BBR-10-HCPT loaded LM was evaluated in nude mice bearing Hep-3B tumor xenograft. The mice were treated with BBR-10-HCPT loaded LM solution, BBR injections, 10-HCPT injection, and saline, respectively. The dose of BBR and 10-HCPT was 3.0 mg/kg and 1.0 mg/kg. Mice were administered preparations twice per week for four weeks. Tumor volume and body weight were measured twice a week. Tumor weight were measured at the end of the experiment. Tumor growth inhibition rate was measured by the following equation:

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