Gene expression and clinical data of the TCGA were downloaded from the PanCanAtlas webpage at Genomic Data Commons repository (https://gdc.cancer.gov/about-data/publications/pancanatlas). Samples diagnosed as lung adenocarcinoma (LUAD) and of the type “primary solid tumor” (code: 01) were included in the analysis. With the exception of two recurrent tumors, all LUAD tumors analyzed in the TCGA could be included (515/517 = 99.6%).

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