Experimental groups were set as follows: normal glucose (NG, 5.5 mmol/L glucose + 10% normal rat serum); high glucose (HG, 30 mmol/L glucose + 10% normal rat serum); Yishen capsule serum group (HG + YS, 30 mmol/L glucose + 10% Yishen capsule serum), high glucose + resveratrol group (HG + R, 30 mmol/L glucose + 10 mmol/L resveratrol + 10% normal rat serum), high glucose + SIRT1 inhibitor group (HG + Ex, 30 mmol/L glucose + 2 μM Ex-527 + normal rat serum).

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