During the treatment period, routine CSF cytology examination was performed before each cycle of the chemotherapy, and fundus examinations and orbital MRI were performed every 4–8 weeks. Follow up every 3 months in the first 1–2 years, every 6 months in the 3–5 years, and once a year from the 6th year after treatment. During follow-up, we monitored patients for tumor recurrence though fundus examinations and orbital MRI. The prognosis of patients was indicated by the overall survival (OS). OS was calculated from the day of first admission to hospital to the time of the last follow-up or death.

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