Human plasma samples were obtained from Peking University Fourth School of Clinical Medicine under the protocol (201904-06) approved by Beijing Jishuitan Hospital Institutional Review Board. For thromboelastography (TEG) and extracorporeal hemodialysis circuit, blood was drawn from healthy volunteers (informed consent was obtained from all subjects). The study was approved by the Institutional Ethics Committee, National Center for Nanoscience and Technology of China (NCNSTIEC0068-0109). Blood draw procedures were achieved in accordance with institutional guidelines. Blood was anticoagulated with 3.2% sodium citrate unless otherwise noted.

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