The smartpca algorithm implemented in EIG v7.2.1 was used to perform the Principal Component Analysis (PCA) for the PGx panels and the genome-wide panel25, 26. The program ADMIXTURE was used to estimate individual ancestry proportions. Supervised and unsupervised analysis were performed with three and four-population models27.

The relative performance of the PGx panels to estimate admixture proportions was evaluated by the correlation of individual admixture proportions (R2 values) obtained with the genome-wide panel versus those obtained with each PGx panel. We also evaluated the differences in mean ancestry proportions obtained with the genome-wide panel and each PGx panel.

Note: The content above has been extracted from a research article, so it may not display correctly.



Q&A
Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.



We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.