Protein selection: selection of protein target was carried out by studying the functional interaction of breast cancer protein through STRING Database. The list of the proteins involved highly in breast cancer protein were retrieved from nodes and edges calculated from the large repositories of protein functions. Molecular Interaction: target protein BRAC2 was retrieved from Protein Databank, 3EU7. Chain A was selected to interact with Selenium Dioxide. SeNP and BRAC2 were interacted using Schrodinger Glide. Molecular dynamics of simulation was performed on docked complex for about 100 ns in water solvent environment. Fluctuation and Deviation dynamics of interacted complex was studied by Macromodel module.

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