Whole exome sequence data from other independent studies

In additional analyses, we also used the most updated whole-exome sequencing (WES) data we could find for each of autism and epilepsy in order to test whether our results were also applicable to a less biased gene set38,61. The 102 autism genes with FDR <  = 0.1 from the autism WES study (see Table S2 in Satterstrom et al., 2020) were used as the autism gene set. The top 200 most significant epilepsy genes outputted by the gene burden test from the epilepsy WES study (see Table S17 in Feng et al., 2019) were used as the epilepsy gene set.

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