Two patients (denoted as patient #1 and patient #2) who underwent split-thickness skin graft surgery following severe burn damage to the skin were recruited, consented, and scanned at two separate time points post-operatively. Both patients had 250 µm-thick autologous grafts excised from the anterior of the femoral thigh and transplanted to the dorsum (patient #1) or ventrum (patient #2) of the right forearm. Both patients received sheet grafts (not meshed). Patient #1 was scanned at 7 and 16 days post-surgery, and patient #2 was scanned at 6 and 14 days post-surgery. Multiple scan sites, i.e., 3–4, were chosen for each patient. For comparative purposes, patient #1 had adjacent burn site and control site scans (contralesional forearm) carried out in addition to three graft site scans. Patient #2 had only three graft scans carried out. The use of OCT laboratory equipment on human subjects was reviewed and approved by the Institutional Review Board of the University of Washington.

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