Statistical analysis was conducted with MedCalc (version 15.2, MedCalc Software bvba, Mariakerke, Belgium) and MATLAB (version 8.5.0 (R2017a), MathWorks Inc., Natick, MA, USA). The relationship between IA size and other factors including the morphological indices of mWT, hemodynamic parameters VIA, VAPA, FlowIA, FlowAPA, PI, and WSSavg, and the demographic parameters of sex, age, smoking history, hypertension, diabetes, and hyperlipidemia was investigated by linear regression analysis (r). The variables which P<0.2 were selected for multivariate logistic regression analysis (partial correlation r). The relationship between WSSavg and mWT was also investigated by linear regression analysis (r). Furthermore, the unpaired two-sample t-test was used to investigate the association between IA size, IA SR, and hemodynamic parameters. The level of statistical significance was set at P<0.05.

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