If two or more of the included studies reported the effect of the exercise intervention on a primary or secondary outcome, we will pool the eligible studies using a meta-analysis approach. Due to the expected heterogeneity of the included studies, we will use the inverse-variance random-effect model.

Revman version 5 will be used to pool estimates of the effect sizes on primary and secondary outcomes. Summary of pooled estimates will be also presented graphically in terms of forest plots.

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