Gene Expression Profiling Interactive Analysis (GEPIA; and GEPIA2 ( were the functional tools for analyzing the prevalence and expression of a gene signature in the Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) samples 18. To further validate the intersecting DEGs, GEPIA and GEPIA2 were used to probe the RNA sequencing expression between BC and normal breast tissues. P<0.05 was considered significant.

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