A PPI network of intersecting DEGs was constructed by an online tool, Search Tool for the Retrieval of Interacting Genes (STRING) 16 version 11.0, to evaluate the protein functions and cellular regulatory mechanisms of DEGs at the molecular level. The Molecular Complex Detection (MCODE) app was a plugin in Cytoscape 17 version 3.7.2 and was applied to check modules of the PPI network. The module with the highest MCODE score is our interesting target.

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