Collection of human cancer genes

We collected and consolidated annotations of human cancer genes from the following sources: (i) 420 human cancer genes from UniProt (31) with keyword “KW-0656” for ONGs and keyword “KW-0043” for tumor suppressors, (ii) 711 known cancer genes and tumor suppressor/ONG annotations from the Network of Cancer Genes (32), (iii) 1217 human TSGs from the Tumor Suppressor Gene database 2.0 (33), (iv) 803 human ONGs from the ONGene database (34), and (v) 239 human ONGs and 251 human tumor suppressors according to annotations from the Tumor Associated Gene database (35).

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