EMSAs were performed using a Light Shift Chemiluminescent EMSA Kit (Thermo, USA) according to the manufacturer’s instructions, with minor modifications. Briefly, ~2 mg of the purified fusion protein was inputted into the binding reaction12, which was performed at 25 °C for 15 min in a thermal cycler (Bio-Rad). Biotin-labeled probes were synthesized by Shanghai Sangon Biotech Co., Ltd.; the sequences of the probes are listed in Supplementary Table S1.

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