Target questions asked the proportion of illnesses transmitted through the 5 major pathways and 6 subpathways for all study pathogens. Study administrators blocked transmission pathways and subpathways for some pathogens based on their microbiology and ecology (Table 4). We created individualized Microsoft Excel version 14.7.7 (http://www.microsoft.com) files with separate sheets for calibration questions, target questions for each assigned pathogen, and additional instructions for each expert. We included verification aids in the worksheets to assist the experts (Appendix 3).

*Blocked indicates pathways blocked by study administrators. AGI, acute gastrointestinal disease; STEC, Shiga toxin–producing Escherichia coli.
†Clinical manifestations of interest for initial elicitation were bacteremia and wound infections.

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