Comparisons between CADASIL, young control, and old control participants were made using Kruskal-Wallis and Mann-Whitney U tests incorporated in SPSS, version 17.0. Correlations between a number of variables including neuronal densities as actual values, SMI32 positive and negative stained axonal densities determined as percent area, and MMSE scores were tested using Spearman's rank order correlation.

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