The miRNA profile and clinical information of PCa patients from TCGA database was download through UCSC Xena HUGO probeMap (https://xenabrowser.net/datapages/). The expression level of miRNA is described as log2 (RPM+1). A total of 491 patients with recurrence-free survival (RFS) information were selected. The MSKCC cohort, also known as GSE21032, was downloaded from the Cbioportal (http://cbio.mskcc.org/), which included miRNA profile (normalized log2 miRNA expression data), and matched clinicopathological features of 105 PCa patients. MSKCC cohort was prepared as the external validation dataset.

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