The miRNA profile and clinical information of PCa patients from TCGA database was download through UCSC Xena HUGO probeMap ( The expression level of miRNA is described as log2 (RPM+1). A total of 491 patients with recurrence-free survival (RFS) information were selected. The MSKCC cohort, also known as GSE21032, was downloaded from the Cbioportal (, which included miRNA profile (normalized log2 miRNA expression data), and matched clinicopathological features of 105 PCa patients. MSKCC cohort was prepared as the external validation dataset.

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