Statistical analysis was performed using Statistica software version 13.0 (StatSoft, Dell Inc., Tulsa, OK, USA) under the license of Wroclaw Medical University, Poland. For the measurable variables, the arithmetic mean (X), median (Mdn), standard deviation (SD), and extreme values (Min and Max) were calculated; for the non-measurable variables, the percentages (%) were calculated. All quantitative variables were tested using the Shapiro-Wilk test to determine their type of distribution. The nonparametric Mann-Whitney U test was used to compare the results between groups (adherent (ADH) versus non - adherent (non-ADH)) for continuous variables, and the chi-squared test was used for categorical data. The Kruskal-Wallis test was used for an intergroup comparison, depending on the answers to the questions. Correlations of BDI, HADS-M, AIS and MS-TAQ domains for ADH and non-ADH patients were calculated using the Spearman correlation coefficient. Forward-stepwise multiple-logistic regression analysis was used to identify factors associated with adherence to recommended treatments. Variables associated with adherence (p < 0.20) were included in the model. For all comparisons, the level of α = 0.05 was assumed.

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