Consecutive CT images were available from 110 patients as of the final observation time point. Two thoracic radiologists (more than 10 years of experience) blinded to the clinical data reviewed the CT images independently and resolved discrepancies by consensus. According to the CT manifestations available from the final observation time point, the presence or absence of the following image features was recorded: ground-glass opacities (GGO), consolidation, mixed GGO and consolidation, traction bronchiectasis, bronchial wall thickening, reticulation, subpleural bands, vascular enlargement, and lesion distribution. The detailed definitions of the above features were as previously described 14. Each lung was divided into three zones: upper (above the carina), middle (below the carina up to the inferior pulmonary vein), and lower (below the inferior pulmonary vein) zones 15. A semi-quantitative score was assigned for each lung zone according to a recent publication regarding chest CT findings of COVID-19 16. Briefly, score 0, 0% involvement; score 1, less than 25% involvement; score 2, 25% to less than 50% involvement; score 3, 50% to less than 75% involvement; and score 4, 75% or greater involvement. Summation of score from all 6 lung zones provided overall CT score (maximal CT score, 24). The CT involvement score < 5 was defined as recovery lesions, while score ≥ 5 was defined as persistent lesions.

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