All animal breeding and experiments were performed in-house and only after approval from the Danish Animal Experiments Inspectorate. Mice deficient in IAPs were bred and maintained at the University of Zurich, Switzerland, and were used after permission from J. Silke (Victoria, Australia) (58). CD4CRE-NIKF/F were bred and maintained at the University of Mainz, Germany (59). C57BL/6 mice were initially purchased from Taconic and bred in-house for all subsequent experiments. RORγt-GFP reporter mice (60) were generously provided by G. Eberl and subsequently bred in-house.

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