DMBA, TPA, BrdU, cycloheximide, 5Z-7-oxozeaenol, and verapamil were from Sigma-Aldrich; MG132, anisomycin, SB202190, and SC409 were from EMD Millipore; D-JNKi was from BML; and murine IL-1α was from R&D Systems. Antibodies against the following proteins were used in immunoblotting after 1:1000 dilution: p38α (sc-535) and p63 4A4 (sc-8431; both from Santa Cruz Biotechnology); p-p38 (9211), p-MK2 (3007), and p-Ser66/68–p63 (4981; all from Cell Signaling Technology); p-Ser301–p63 (PA5-39827) and p-Ser361–p63 (PA5-38380; both from Thermo Fisher Scientific); and actin (A4700; Sigma-Aldrich). Antibodies specific to the following proteins were used in immunofluorescence staining after 1:50 to 1:1000 dilution: p38α (sc-535), p63 H-137 (sc-8343), and p63 4A4 (sc-8431; all from Santa Cruz Biotechnology); p-p38 (9211) and p-Ser66/68–p63 (4981; both from Cell Signaling Technology); Ki67 (ab16667) and MMP13 (ab39012; both from Abcam); KRT14 (PRB-155P) and KRT15 (PCK-153P; both from Covance); CD3e (SP7) and KRT1 (ab9286; both from Abcam); and Ly6G/Gr-1 (553125; BD Biosciences). Hoechst 33324 and antibodies conjugated with Alexa Fluor 488 or Alexa Fluor 595 were from Molecular Probes.

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