NAADP-AM and NAADP were synthesized in-house (26, 99). Other drugs were purchased from the following suppliers: Abcam (LY341495, CGP 55845, D-AP5, Ned-19, JNJ16259685, MPEP, QX314, and TTX), Sigma-Aldrich (ryanodine, bafilomycin A1, picrotoxin, NBQX, NAAD and BAPTA, BAPTA-AM, and EGTA-AM), Santa Cruz Biotechnology (GPN), Thermo Fisher Scientific (OBG-1), and Tocris (U73122 and U73343).

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