The Z′ values were calculated using the equation Z=13σ++3σMean+Mean (79). σ+ is the SD of the negative control group (negative control groups in the luciferase reporter assay and AlamarBlue cytotoxicity assay for each cell line as defined above), σ is the SD of the positive control group (positive control groups in the luciferase reporter assay and AlamarBlue cytotoxicity assay for each cell line as defined above), Mean+ is the mean of the negative control group, and Mean is the mean of the positive control group.

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