Statistical analysis in the present study was performed using SPSS version 18.0 software (SPSS Inc.). Results were expressed as mean value ± SD. The significance of mean values between two groups was determined by Student’s t test. All differences were two-sided. The significance of the results from patient specimens was analyzed by the χ2 test or the Pearson’s correlation coefficient test. The effects of treatments on tumor size were evaluated using two-way analysis of variance (ANOVA) and Fisher’s post hoc test. A P value of <0.05 was considered statistically significant.

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