Inhibition of molecular pathways regulating properties of HMSCs in MBs

To interrogate the contribution of signaling related to anti-inflammatory molecule production (COX-2 and NF-κB) or molecular pathways regulated by the cell structural organization (Notch, ROCK, and F-actin), several small molecules inducing their inhibition were added to the culture medium (table S1). For all the conditions, the final concentration of DMSO was below 0.1% (v/v) in the culture medium.

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