All experiments were performed on adult male mice (8 to 14 weeks of age) and were randomly assigned to control or experimental groups and device implantation. Sample sizes were determined from preliminary experiments using the software G*Power for the appropriate type of statistical comparison. For place preference and thermal sensitivity assays, data were excluded from animals where the device was obviously damaged. All data were collected in a nonbiased manner, and the experimenter was blinded to treatment for histological analysis and to animal genotype for the place preference assay. One-way and two-way analyses of variance (ANOVAs) were performed as appropriate. P values <0.05 were considered statistically significant. All graphs are represented as means ± SEM. Further statistical details can be found in tables S3 and S4.

Note: The content above has been extracted from a research article, so it may not display correctly.



Q&A
Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.



We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.