The plots in fig. S5 were made by modifications of functions from the “matchSCore” package in R (46). That is, Jaccard indices were calculated comparing all markers for each node with an average log fold change of >1, in every species, to those of each node in every other. Homolog conversion (see above) was performed before testing. The heat map representation of these data was made using the “complexHeatmap” package.

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