Thirty-four patients with tumor stages III and IV MBC were recruited for analysis of CTCs and DTCs at Shanghai General Hospital from September 2015 to April 2017. Metastasis sites were determined by computed tomography, magnetic resonance imaging, and bone scintigraphy. TNM (Tumor-Node-Metastasis) staging was assessed and given according to the Union for International Cancer Control 2009 guidelines. Patients were followed up until January 2018.

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