The study involving human subjects adhered to the tenets of the Declaration of Helsinki and was approved by the local ethics committee of the Swiss Department of Health on research involving human subjects (CER-VD N°340/15). For vitreous and SRFs, written informed consent was obtained from all patients after detailed explanation of the purpose and methods of the study. All experimental procedures performed using rats and mice were approved by the local ethics committee of the Charles Darwin European Council, University of Paris-Descartes. Experiments were performed in accordance with the Association for Research in Vision and Ophthalmology statement for the use of animals in ophthalmic and vision research.

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