Group-level values introduced to the statistical analyses are reported in Fig. 5. Preprocessed, WM-corrected CBF values acquired before and during tES were compared using paired t test statistics for the entire sample (n = 10; 7 before surgery, 3 after surgery), with an α level of 0.05. The analysis was conducted separately for each ROI, i.e., solid tumor (surgical border/residual solid tumor for postsurgery analyses), edema, and necrotic core. Separate paired t test analyses were conducted for ipsilateral/contralateral control regions as well. The same model was used to look at before versus during tES differences in fALFF and ReHo values extracted from solid tumor, edema, and necrotic core. Given the small sample size and independence of each analysis, no correction for multiple comparisons was applied.

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