To control for the selectivity and specificity of stimulation on CBF, additional rs-fMRI scans were added to the protocol. ReHo and fALFF indices were extracted with CONN software (www.conn-toolbox.org/). ALFF was considered an index of regional SNA, in contrast to the more classical functional connectivity analysis that provide insight into interregional interactions between areas. fALFF used the ratio of the power spectrum of low frequency (0.01 to 0.08 Hz) to that of the entire frequency range (e.g., 0 to 0.25 Hz for a TR = 2 s) of BOLD signal, allowing to discriminate the signal from liquor cisterns to cortical regions. On the other hand, regional homogeneity (ReHo) was thought to reflect neural synchronization of a given voxel with its neighboring voxels, with higher ReHo value indicating high regional synchronization. In the present analysis, ReHo was calculated according to previous literature calculating the Kendall’s coefficient of concordance of the time series of a voxel in relation to those of 26 nearest neighbors.

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