The THP-1 (human acute monocytic leukemia cell line), PC12 cell line (a neuron-like rat pheochromocytoma cell line), HL-60 cell line (human promyelocytic leukemia cell line), and HBMEC were from American Type Culture Collection. Adult male Sprague-Dawley rats (250 to 300 g, 7 to 8 weeks) and male BALB/c nude mice (25 to 30 g, 7 to 8 weeks) were from Sino-British SIPPR/BK Lab Animal Co. Ltd. The animal experiment protocol was approved by the Animal Experimentation Ethics Committee of Fudan University.

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